Tannic acid
Depinar (tannic acid) is an unknown pharmaceutical. Tannic acid was first approved as Depinar on 1982-01-01. It is known to target anoctamin-1.
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Cyanocobalamin
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Tannic acid
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Zinc acetate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DEPINAR | Armour Pharmaceutical | N-011208 DISCN | 1982-01-01 | 1 products |
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EMA
Brand Name | Status | Last Update |
|---|---|---|
| nitrotan | OTC monograph not final | 2013-07-26 |
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Agency Specific
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Clinical
Clinical Trials
5950 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 7 | 5 | 8 | 13 | 169 | 201 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 13 | 7 | 15 | 17 | 133 | 181 |
| Syndrome | D013577 | — | — | 10 | 35 | 25 | 11 | 96 | 169 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 8 | 4 | 14 | 15 | 84 | 125 |
| Stroke | D020521 | EFO_0000712 | I63.9 | 2 | 8 | 12 | 7 | 93 | 120 |
| Hypertension | D006973 | EFO_0000537 | I10 | 1 | 7 | 12 | 12 | 71 | 102 |
| Cognitive dysfunction | D060825 | — | G31.84 | 4 | 11 | 5 | 7 | 78 | 102 |
| Depression | D003863 | — | F33.9 | 6 | 2 | 6 | 3 | 85 | 102 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 3 | 10 | 41 | 11 | 35 | 98 |
| Wounds and injuries | D014947 | — | T14.8 | 6 | 13 | 3 | 5 | 75 | 97 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Exercise | D015444 | EFO_0000483 | — | — | 1 | 2 | — | 98 | 101 |
| Covid-19 | D000086382 | — | U07.1 | — | 10 | 9 | — | 46 | 64 |
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | 2 | — | 1 | — | 41 | 44 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | 3 | 2 | 1 | — | 36 | 41 |
| Obstructive lung diseases | D008173 | — | — | — | 4 | 2 | — | 31 | 37 |
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | 2 | 2 | 3 | — | 29 | 36 |
| Inflammation | D007249 | MP_0001845 | — | 3 | 5 | 2 | — | 25 | 32 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | — | 1 | — | 30 | 31 |
| Premature birth | D047928 | EFO_0003917 | O60 | 1 | 2 | 1 | — | 27 | 30 |
| Obstructive sleep apnea | D020181 | EFO_0003918 | G47.33 | 3 | 1 | 1 | — | 26 | 30 |
Show 297 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aging | D000375 | GO_0007568 | R41.81 | 3 | 3 | — | — | 48 | 54 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 2 | 2 | — | — | 37 | 41 |
| Neck pain | D019547 | — | M54.2 | — | 1 | — | — | 38 | 39 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | 3 | 2 | — | — | 28 | 33 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | 4 | 4 | — | — | 20 | 27 |
| Pediatric obesity | D063766 | — | — | — | 1 | — | — | 23 | 24 |
| Sleep wake disorders | D012893 | — | G47 | 3 | 1 | — | — | 19 | 23 |
| Chronic disease | D002908 | — | — | — | 1 | — | — | 21 | 22 |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | 2 | 1 | — | — | 15 | 18 |
| Autism spectrum disorder | D000067877 | — | F84.0 | 1 | 1 | — | — | 15 | 17 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cerebral palsy | D002547 | — | G80 | 3 | — | — | — | 28 | 31 |
| Sleep | D012890 | GO_0030431 | — | 4 | — | — | — | 20 | 24 |
| Mental health | D008603 | EFO_0003935 | — | 1 | — | — | — | 11 | 12 |
| Healthy diet | D000072001 | — | — | 1 | — | — | — | 10 | 11 |
| Pain management | D059408 | — | — | 2 | — | — | — | 8 | 10 |
| Problem behavior | D000066553 | — | — | 1 | — | — | — | 9 | 10 |
| Laparoscopic cholecystectomy | D017081 | — | — | 2 | — | — | — | 7 | 9 |
| Oxygen inhalation therapy | D010102 | — | — | 1 | — | — | — | 8 | 9 |
| Respiration disorders | D012120 | — | J00-J99 | 1 | — | — | — | 7 | 8 |
| Bronchopulmonary dysplasia | D001997 | — | P27.8 | 1 | — | — | — | 6 | 7 |
Show 47 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sedentary behavior | D057185 | — | — | — | — | — | — | 54 | 54 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | — | — | 42 | 42 |
| Chronic pain | D059350 | — | — | — | — | — | — | 28 | 28 |
| Emergencies | D004630 | — | — | — | — | — | — | 20 | 20 |
| Health behavior | D015438 | — | — | — | — | — | — | 20 | 20 |
| Weight gain | D015430 | — | — | — | — | — | — | 15 | 15 |
| Psychological stress | D013315 | — | — | — | — | — | — | 15 | 15 |
| Scoliosis | D012600 | EFO_0004273 | M41 | — | — | — | — | 14 | 14 |
| Dental caries | D003731 | EFO_0003819 | K02 | — | — | — | — | 14 | 14 |
| Disease progression | D018450 | — | — | — | — | — | — | 13 | 13 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Tannic acid |
| INN | _ |
| Description | Tannic acid is a specific form of tannin, a type of polyphenol. Its weak acidity (pKa around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C76H52O46, which corresponds with decagalloyl glucose, but in fact it is a mixture of polygalloyl glucoses or polygalloyl quinic acid esters with the number of galloyl moieties per molecule ranging from 2 up to 12 depending on the plant source used to extract the tannic acid. Commercial tannic acid is usually extracted from any of the following plant parts: Tara pods (Caesalpinia spinosa), gallnuts from Rhus semialata or Quercus infectoria or Sicilian sumac leaves (Rhus coriaria).
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1 |
Identifiers
| PDB | — |
| CAS-ID | 1401-55-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL506247 |
| ChEBI ID | 81066 |
| PubChem CID | 16129778 |
| DrugBank | — |
| UNII ID | 28F9E0DJY6 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ANO1
ANO1
Organism
Homo sapiens
Gene name
ANO1
Gene synonyms
DOG1, ORAOV2, TAOS2, TMEM16A
NCBI Gene ID
Protein name
anoctamin-1
Protein synonyms
anoctamin 1, calcium activated chloride channel, Ca2+-activated Cl- channel, calcium activated chloride channel, Discovered on gastrointestinal stromal tumors protein 1, oral cancer overexpressed 2, Oral cancer overexpressed protein 2, Transmembrane protein 16A, transmembrane protein 16A (eight membrane-spanning domains), Tumor-amplified and overexpressed sequence 2
Uniprot ID
Mouse ortholog
Ano1 (101772)
anoctamin-1 (Q99JK1)
Variants
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Financial
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Trends
PubMed Central
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Safety
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Adverse Events
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11 adverse events reported
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