Tannic acid
Depinar (tannic acid) is an unknown pharmaceutical. Tannic acid was first approved as Depinar on 1982-01-01. It is known to target anoctamin-1.
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Cyanocobalamin
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Tannic acid
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Zinc acetate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DEPINAR | Armour Pharmaceutical | N-011208 DISCN | 1982-01-01 | 1 products |
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Brand Name | Status | Last Update |
|---|---|---|
| nitrotan | OTC monograph not final | 2013-07-26 |
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Agency Specific
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Clinical
Clinical Trials
6690 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 9 | 7 | 9 | 13 | 194 | 230 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 11 | 6 | 10 | 11 | 123 | 157 |
| Syndrome | D013577 | — | — | 10 | 22 | 18 | 9 | 87 | 139 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 8 | 5 | 15 | 17 | 91 | 136 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 10 | 12 | 5 | 109 | 134 |
| Depression | D003863 | — | F33.9 | 5 | 2 | 6 | 2 | 94 | 109 |
| Cognitive dysfunction | D060825 | — | G31.84 | 5 | 13 | 5 | 6 | 82 | 108 |
| Overweight | D050177 | — | E66.3 | 2 | 3 | 3 | 2 | 95 | 104 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 6 | 10 | 10 | 71 | 96 |
| Respiratory insufficiency | D012131 | — | J96.9 | 1 | 8 | 8 | 3 | 73 | 92 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Exercise | D015444 | EFO_0000483 | — | — | 1 | 2 | — | 114 | 117 |
| Covid-19 | D000086382 | — | U07.1 | — | 10 | 10 | — | 44 | 63 |
| Motor activity | D009043 | EFO_0003940 | — | 1 | — | 1 | — | 59 | 61 |
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | 2 | 2 | 3 | — | 45 | 52 |
| Mental disorders | D001523 | EFO_0000677 | F91.9 | 1 | 1 | 2 | — | 38 | 41 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | — | 1 | — | 37 | 38 |
| Obstructive lung diseases | D008173 | — | — | — | 4 | 2 | — | 30 | 36 |
| Sclerosis | D012598 | — | — | 2 | 7 | 3 | — | 24 | 34 |
| Premature birth | D047928 | EFO_0003917 | O60 | 1 | 1 | 2 | — | 30 | 33 |
| Cerebral palsy | D002547 | — | G80 | 3 | — | 1 | — | 28 | 32 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aging | D000375 | GO_0007568 | R41.81 | 3 | 3 | — | — | 51 | 57 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | 1 | — | — | 51 | 52 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 4 | 2 | — | — | 43 | 49 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | 3 | 1 | — | — | 41 | 45 |
| Neck pain | D019547 | — | M54.2 | — | 1 | — | — | 39 | 40 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | 3 | 3 | — | — | 30 | 36 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | 4 | 3 | — | — | 23 | 29 |
| Pediatric obesity | D063766 | — | — | — | 1 | — | — | 23 | 24 |
| Autism spectrum disorder | D000067877 | — | F84.0 | 1 | 1 | — | — | 19 | 21 |
| Dyspnea | D004417 | — | R06.0 | — | 1 | — | — | 17 | 18 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sleep | D012890 | GO_0030431 | — | 4 | — | — | — | 24 | 28 |
| Pain management | D059408 | — | — | 2 | — | — | — | 14 | 16 |
| Mental health | D008603 | EFO_0003935 | — | 1 | — | — | — | 13 | 14 |
| Healthy diet | D000072001 | — | — | 1 | — | — | — | 11 | 12 |
| Laparoscopic cholecystectomy | D017081 | — | — | 2 | — | — | — | 9 | 11 |
| Problem behavior | D000066553 | — | — | 1 | — | — | — | 8 | 9 |
| Oxygen inhalation therapy | D010102 | — | — | 1 | — | — | — | 8 | 9 |
| Hyperthermia | D000084462 | — | — | 1 | — | — | — | 8 | 9 |
| Respiration disorders | D012120 | — | J00-J99 | 1 | — | — | — | 6 | 7 |
| Sleep deprivation | D012892 | — | F51.12 | 2 | — | — | — | 4 | 6 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sedentary behavior | D057185 | — | — | — | — | — | — | 66 | 66 |
| Chronic pain | D059350 | — | — | — | — | — | — | 36 | 36 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | — | — | 25 | 25 |
| Health behavior | D015438 | — | — | — | — | — | — | 20 | 20 |
| Dental caries | D003731 | EFO_0003819 | K02 | — | — | — | — | 17 | 17 |
| Psychological stress | D013315 | — | — | — | — | — | — | 16 | 16 |
| Disease progression | D018450 | — | — | — | — | — | — | 14 | 14 |
| Feeding behavior | D005247 | — | — | — | — | — | — | 14 | 14 |
| Deglutition disorders | D003680 | — | R13.1 | — | — | — | — | 14 | 14 |
| Scoliosis | D012600 | EFO_0004273 | M41 | — | — | — | — | 14 | 14 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Tannic acid |
| INN | _ |
| Description | Tannic acid is a specific form of tannin, a type of polyphenol. Its weak acidity (pKa around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C76H52O46, which corresponds with decagalloyl glucose, but in fact it is a mixture of polygalloyl glucoses or polygalloyl quinic acid esters with the number of galloyl moieties per molecule ranging from 2 up to 12 depending on the plant source used to extract the tannic acid. Commercial tannic acid is usually extracted from any of the following plant parts: Tara pods (Caesalpinia spinosa), gallnuts from Rhus semialata or Quercus infectoria or Sicilian sumac leaves (Rhus coriaria).
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1 |
Identifiers
| PDB | — |
| CAS-ID | 1401-55-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL506247 |
| ChEBI ID | 81066 |
| PubChem CID | 16129778 |
| DrugBank | — |
| UNII ID | 28F9E0DJY6 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ANO1
ANO1
Organism
Homo sapiens
Gene name
ANO1
Gene synonyms
DOG1, ORAOV2, TAOS2, TMEM16A
NCBI Gene ID
Protein name
anoctamin-1
Protein synonyms
anoctamin 1, calcium activated chloride channel, Ca2+-activated Cl- channel, calcium activated chloride channel, Discovered on gastrointestinal stromal tumors protein 1, oral cancer overexpressed 2, Oral cancer overexpressed protein 2, Transmembrane protein 16A, transmembrane protein 16A (eight membrane-spanning domains), Tumor-amplified and overexpressed sequence 2
Uniprot ID
Mouse ortholog
Ano1 (101772)
anoctamin-1 (Q99JK1)
Variants
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Financial
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Trends
PubMed Central
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Safety
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Adverse Events
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11 adverse events reported
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