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Drug ReportsTannic acid
Tannic acid
Depinar (tannic acid) is an unknown pharmaceutical. Tannic acid was first approved as Depinar on 1982-01-01. It is known to target anoctamin-1.
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cyanocobalamin
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Tannic acid
+
Zinc acetate
Tradename
Company
Number
Date
Products
DEPINARArmour PharmaceuticalN-011208 DISCN1982-01-01
1 products
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FDA
EMA
Brand Name
Status
Last Update
nitrotanOTC monograph not final2013-07-26
Indications
FDA
EMA
No data
Agency Specific
FDA
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ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
5227 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.964611154180
Diabetes mellitusD003920HP_0000819E08-E131371417123170
SyndromeD0135771033241084153
Type 2 diabetes mellitusD003924EFO_0001360E1184131476115
StrokeD020521EFO_0000712I63.92812675101
HypertensionD006973EFO_0000537I101512126493
Kidney diseasesD007674EFO_0003086N083104093191
DepressionD003863F33.952827590
Cognitive dysfunctionD060825HP_0001268G31.8428466886
Wounds and injuriesD014947T14.8511346685
Show 425 more
Indications Phases 3
Indications Phases 2
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cerebral palsyD002547G8032326
SleepD012890GO_003043121820
Oxygen inhalation therapyD010102178
Respiration disordersD012120J00-J99178
Laparoscopic cholecystectomyD017081167
Bronchopulmonary dysplasiaD001997P27.8167
Aortic aneurysmD001014EFO_0001666I71.9145
Pain managementD059408145
Sleep deprivationD012892F51.12145
Driving under the influenceD000066448314
Show 34 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sedentary behaviorD0571854848
Metabolic syndromeD024821EFO_0000195E88.8104141
Chronic painD059350HP_00125322525
Bone fracturesD050723EFO_0003931T14.82121
Health behaviorD0154382020
EmergenciesD0046301919
Weight gainD015430HP_00043241515
HypercapniaD0069351515
Neurocognitive disordersD019965F091313
Psychological stressD0133151313
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTannic acid
INN
Description
Tannic acid is a specific form of tannin, a type of polyphenol. Its weak acidity (pKa around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C76H52O46, which corresponds with decagalloyl glucose, but in fact it is a mixture of polygalloyl glucoses or polygalloyl quinic acid esters with the number of galloyl moieties per molecule ranging from 2 up to 12 depending on the plant source used to extract the tannic acid. Commercial tannic acid is usually extracted from any of the following plant parts: Tara pods (Caesalpinia spinosa), gallnuts from Rhus semialata or Quercus infectoria or Sicilian sumac leaves (Rhus coriaria).
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=C(OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1
Identifiers
PDB
CAS-ID1401-55-4
RxCUI
ChEMBL IDCHEMBL506247
ChEBI ID81066
PubChem CID16129778
DrugBank
UNII ID
Target
Agency Approved
No data
Alternate
ANO1
ANO1
Organism
Homo sapiens
Gene name
ANO1
Gene synonyms
DOG1, ORAOV2, TAOS2, TMEM16A
NCBI Gene ID
Protein name
anoctamin-1
Protein synonyms
anoctamin 1, calcium activated chloride channel, Ca2+-activated Cl- channel, calcium activated chloride channel, Discovered on gastrointestinal stromal tumors protein 1, oral cancer overexpressed 2, Oral cancer overexpressed protein 2, Transmembrane protein 16A, transmembrane protein 16A (eight membrane-spanning domains), Tumor-amplified and overexpressed sequence 2
Uniprot ID
Mouse ortholog
Ano1 (101772)
anoctamin-1 (Q99JK1)
Variants
No data
Financial
No data
Trends
PubMed Central
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Safety
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11 adverse events reported
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